Combination Therapy Cancer Treatment In India At Mumbai And Bangalore At Low Cost.

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Submitted by: P Nagpal Nagpal

Combination Therapy

Combination therapy may benefit patients with specific genetic subtype of non-small cell lung cancer, study finds

Even when their tumors are shrinking in response to therapy, some non-small cell lung cancer (NSCLC) patients have a scattering of cancer cells that are undeterred by the drug, causing the tumor to resume its growth, Dana-Farber Cancer Institute and Massachusetts General Hospital (MGH) Cancer Center scientists report in the January issue of Cancer Cell. The findings suggest that identifying such patients and treating them with a combination of drugs from the very start of therapy can produce longer remissions.

One of the triggers for resistance, the researchers found, is HGF, a ligand or “hook” that activates the MET protein.

When activated, HGF works through two entirely different channels to produce drug resistance, the authors report. First, it can generate cell-growth signals through a protein called GAB1. Second, it expands the number of MET-amplified cancer cells, ensuring they will become the dominant type in the lung tumors.

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“Not only can HGF spur cell growth on its own, it can speed up the process by which MET-amplified cells emerge and take over the composition of the tumor.

Combination therapy may benefit patients with specific genetic subtype of non-small cell lung cancer, study finds

Even when their tumors are shrinking in response to therapy, some non-small cell lung cancer (NSCLC) patients have a scattering of cancer cells that are undeterred by the drug, causing the tumor to resume its growth, Dana-Farber Cancer Institute and Massachusetts General Hospital (MGH) Cancer Center scientists report in the January issue of Cancer Cell.

The findings suggest that identifying such patients and treating them with a combination of drugs from the very start of therapy can produce longer remissions.

One of the triggers for resistance, the researchers found, is HGF, a ligand or “hook” that activates the MET protein.

In about 20 percent of NSCLC patients who are resistant to Tarceva the mechanism is amplification of MET, and in another 20 percent it may involve HGF.

The findings suggest that patients whose NSCLC tumors harbor even a few MET-amplified cells prior to treatment would benefit from drugs that specifically target those cells, in combination with a tyrosine kinase inhibitor. J nne notes that such drugs are already being studied in clinical trials.

A thorough analysis of a patient’s cancer prior to treatment can establish how it would ultimately develop resistance to therapy, allowing us to tailor treatment with greater precision to prevent resistance.

“For example, cancers found to harbor a small population of cells with pre-existing MET amplification will likely benefit from adding MET inhibitors to initial treatment. Those without such cells may not benefit, and these patients can avoid the added toxicity of MET inhibitors and instead focus on other strategies to prevent their cancers from becoming resistant.”

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About the Author: Pankaj Nagpal – About the Author:Welcome to World Class Treatment and Surgery by We Care Health Services, India. Contact Us : www.indiahospital

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FDA says Coca-Cola’s Diet Coke Plus is misbranded

Thursday, December 25, 2008 

The US Food and Drug Administration has written a warning letter to The Coca-Cola Company that Diet Coke Plus violates the Federal Food, Drug, and Cosmetic Act’s guidelines. The December 10 letter, signed by Roberta Wagner, director of the office of compliance at the Center of Food Safety and Applied Nutrition, says Coca-Cola should “take prompt action to correct these violations.”

The product’s label describes the drink as “Diet Coke with Vitamins and Minerals.” FDA said the soft drink does not have enough nutrients to justify the use of the word “plus” in its trade name. According to statute, foods must contain at least 10 per cent more of the Reference Daily Intake (RDI) or Daily Reference Value (DRV) for a given nutrient “than an appropriate reference food” in order to be called “plus” legally.

The FDA also advised “it is inappropriate to add extra nutrients to snack foods such as carbonated beverages.” The FDA warns Coca-Cola and asks it to revise the drink’s labeling and inform the agency of its reply regarding how it plans to fix the violation, within 15 days of receiving the warning. Coca-Cola says it will submit a reply to the FDA in early January, but currently has no plans to alter the label.

The US Federal Food, Drug, and Cosmetic Act (FFDCA, FDCA, or FD&C), is a set of laws passed by Congress in 1938 giving authority to the Food and Drug Administration (FDA) to oversee the safety of food, drugs, and cosmetics. A principal author of this law was Royal S. Copeland, a three-term U.S. Senator from New York, whose concerns about drug safety stemmed from the fact that he was also a homeopathic physician. The act has been amended many times, most recently to add requirements about bioterrorism preparations.

The Coca-Cola Company issued a statement saying, “This does not involve any health or safety issues, and we believe the label on Diet Coke Plus complies with FDA’s policies and regulations.”

The Coca-Cola Company is the world’s largest beverage company, largest manufacturer, distributor and marketer of non-alcoholic beverage concentrates and syrups in the world, and one of the largest corporations in the United States. The company is best known for its flagship product Coca-Cola, invented by pharmacist John Stith Pemberton in 1886. Diet Coke Plus (also known as Coca Cola Light Plus) was released in the United Kingdom in October 2007.

Forbes has reported that “Coca-Cola has been on a crusade to revamp its image from a purveyor of highly sweetened, fattening products to a more family-friendly image of low-calorie, nutritional drinks. Its violation of the Federal Food, Drug and Cosmetic Act could mean hefty fines and a seizure of product from the pop king, but often these sorts of issues are resolved without incident.”

FDA says Coca-Cola’s Diet Coke Plus is misbranded

Thursday, December 25, 2008 

The US Food and Drug Administration has written a warning letter to The Coca-Cola Company that Diet Coke Plus violates the Federal Food, Drug, and Cosmetic Act’s guidelines. The December 10 letter, signed by Roberta Wagner, director of the office of compliance at the Center of Food Safety and Applied Nutrition, says Coca-Cola should “take prompt action to correct these violations.”

The product’s label describes the drink as “Diet Coke with Vitamins and Minerals.” FDA said the soft drink does not have enough nutrients to justify the use of the word “plus” in its trade name. According to statute, foods must contain at least 10 per cent more of the Reference Daily Intake (RDI) or Daily Reference Value (DRV) for a given nutrient “than an appropriate reference food” in order to be called “plus” legally.

The FDA also advised “it is inappropriate to add extra nutrients to snack foods such as carbonated beverages.” The FDA warns Coca-Cola and asks it to revise the drink’s labeling and inform the agency of its reply regarding how it plans to fix the violation, within 15 days of receiving the warning. Coca-Cola says it will submit a reply to the FDA in early January, but currently has no plans to alter the label.

The US Federal Food, Drug, and Cosmetic Act (FFDCA, FDCA, or FD&C), is a set of laws passed by Congress in 1938 giving authority to the Food and Drug Administration (FDA) to oversee the safety of food, drugs, and cosmetics. A principal author of this law was Royal S. Copeland, a three-term U.S. Senator from New York, whose concerns about drug safety stemmed from the fact that he was also a homeopathic physician. The act has been amended many times, most recently to add requirements about bioterrorism preparations.

The Coca-Cola Company issued a statement saying, “This does not involve any health or safety issues, and we believe the label on Diet Coke Plus complies with FDA’s policies and regulations.”

The Coca-Cola Company is the world’s largest beverage company, largest manufacturer, distributor and marketer of non-alcoholic beverage concentrates and syrups in the world, and one of the largest corporations in the United States. The company is best known for its flagship product Coca-Cola, invented by pharmacist John Stith Pemberton in 1886. Diet Coke Plus (also known as Coca Cola Light Plus) was released in the United Kingdom in October 2007.

Forbes has reported that “Coca-Cola has been on a crusade to revamp its image from a purveyor of highly sweetened, fattening products to a more family-friendly image of low-calorie, nutritional drinks. Its violation of the Federal Food, Drug and Cosmetic Act could mean hefty fines and a seizure of product from the pop king, but often these sorts of issues are resolved without incident.”

FDA says Coca-Cola’s Diet Coke Plus is misbranded

Thursday, December 25, 2008 

The US Food and Drug Administration has written a warning letter to The Coca-Cola Company that Diet Coke Plus violates the Federal Food, Drug, and Cosmetic Act’s guidelines. The December 10 letter, signed by Roberta Wagner, director of the office of compliance at the Center of Food Safety and Applied Nutrition, says Coca-Cola should “take prompt action to correct these violations.”

The product’s label describes the drink as “Diet Coke with Vitamins and Minerals.” FDA said the soft drink does not have enough nutrients to justify the use of the word “plus” in its trade name. According to statute, foods must contain at least 10 per cent more of the Reference Daily Intake (RDI) or Daily Reference Value (DRV) for a given nutrient “than an appropriate reference food” in order to be called “plus” legally.

The FDA also advised “it is inappropriate to add extra nutrients to snack foods such as carbonated beverages.” The FDA warns Coca-Cola and asks it to revise the drink’s labeling and inform the agency of its reply regarding how it plans to fix the violation, within 15 days of receiving the warning. Coca-Cola says it will submit a reply to the FDA in early January, but currently has no plans to alter the label.

The US Federal Food, Drug, and Cosmetic Act (FFDCA, FDCA, or FD&C), is a set of laws passed by Congress in 1938 giving authority to the Food and Drug Administration (FDA) to oversee the safety of food, drugs, and cosmetics. A principal author of this law was Royal S. Copeland, a three-term U.S. Senator from New York, whose concerns about drug safety stemmed from the fact that he was also a homeopathic physician. The act has been amended many times, most recently to add requirements about bioterrorism preparations.

The Coca-Cola Company issued a statement saying, “This does not involve any health or safety issues, and we believe the label on Diet Coke Plus complies with FDA’s policies and regulations.”

The Coca-Cola Company is the world’s largest beverage company, largest manufacturer, distributor and marketer of non-alcoholic beverage concentrates and syrups in the world, and one of the largest corporations in the United States. The company is best known for its flagship product Coca-Cola, invented by pharmacist John Stith Pemberton in 1886. Diet Coke Plus (also known as Coca Cola Light Plus) was released in the United Kingdom in October 2007.

Forbes has reported that “Coca-Cola has been on a crusade to revamp its image from a purveyor of highly sweetened, fattening products to a more family-friendly image of low-calorie, nutritional drinks. Its violation of the Federal Food, Drug and Cosmetic Act could mean hefty fines and a seizure of product from the pop king, but often these sorts of issues are resolved without incident.”

What To See In Pattaya City

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Submitted by: Nicholas Jarder

Pattaya City is undoubtedly one of the liveliest and most vibrant cities in the world, with a broad range of attractions for both the young and the old. While it has developed a reputation as a wild site for fun-loving tourists, in recent years it has tried to moderate this and position itself as a more family-friendly destination. Here are some of the attractions in Pattaya that the whole family can enjoy.

1. Tiffany s Ladyboy Cabaret Show is the first cabaret show in Southeast Asia performed exclusively by transvestites. Starting in 1974 with only three performers, the Tiffany s show cast has since grown to more than 100 performers adorned in elaborate costumes performing in the company s own 1,000-seat theater. With any raunchiness toned down, the show is now deemed safe for all ages and encompasses a wide range of styles ranging from a history of Siam told through dance to Broadway musicals and even a Bollywood-style number.

2. The Ripley s Believe It or Not museum features over 300 exhibits from the collection of Robert Ripley, the creator of the internationally-famed books about world oddities. Located at the third floor of the Royal Garden Plaza, the museum has ten galleries featuring all manner of strange and shocking exhibits, such as genuine human shrunken heads and a mask made entirely of human skin, as well as more benign curiosities such as a model of the Titanic made from more than a million matchsticks.

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3. The Alangkarn Theater is a must for tourists wanting to see the hottest cultural shows in Pattaya City. The 2,000-seat theater is adorned with modern Thai d cor and features the 70 meter long Hexa Stage which has a host of state-of-the-art facilities such as a gigantic movie screen and high-tech light and sound systems that include digital synchronized pyrotechnics as well as multi-colored laser animation. And viewers can treat themselves to delicious local and international cuisine at the theater restaurant before or after the show or go shopping for souvenirs in the Cultural Rostrum, which features a wide variety of traditional handicrafts.

4. The Marine Science Aquarium and Museum of the Bang Sen Institute of Marine Science is the ideal educational destination for visitors wanting to learn more about local marine life. Designed to educate visitors about marine life and the marine environment, the Marine Science Aquarium features a large collection of marine life, including crustaceans, fish and vegetation. And the museum is conveniently located near the Bangsaen Beach, one of Pattaya s most laid-back and affordable beaches.

5. Mini Siam in Pattaya City is one of the world s most unique attractions a park that features over a hundred miniature replicas of famous sites worldwide. Divided into two sites Mini Siam and Mini Europe you can not only see such familiar attractions as the Statue of Liberty and the Eiffel Tower, but also famous structures from Thai history, including the Temple of the Emerald Buddha and Sukhotai s Wat Mahathat to more modern creations like the Hualamphong Train Station and the Rama IX suspension-cable bridge.

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Acting teacher and director Milton Katselas dies at age 75

Tuesday, October 28, 2008 

Acting teacher and director Milton Katselas died Friday at age 75, after suffering from heart failure at Cedars-Sinai Medical Center in Los Angeles, California. He began the Beverly Hills Playhouse in 1978 and taught acting classes there to noted actors including George Clooney and Gene Hackman. Katselas is survived by a sister and two brothers.

Katselas directed an off-Broadway production of Edward Albee’s The Zoo Story, and received a Tony Award nomination for his 1969 direction of Butterflies are Free. Actress Blythe Danner won a Tony Award for her role in Butterflies are Free under Katselas’ direction. He moved to California to direct the film version of that play, and went on to direct films and television movies. Actress Eileen Heckart received an Academy Award for her role in the film version of Butterflies are Free.

Katselas directed the San Francisco and Los Angeles productions of the play P.S. Your Cat Is Dead! by playwright James Kirkwood, Jr. In his author’s notes in the publication of the script, Kirkwood acknowledged Katselas, and wrote that the plays were “directed with incredible energy and enthusiasm by Milton Katselas, to whom I am extremely indebted”.

Katselas directed the television movie Strangers: Story of a Mother and Daughter, and actress Bette Davis received an Emmy Award for her role in the movie. Katselas taught many famous actors including Michelle Pfeiffer, Richard Gere, Robert Duvall, Jack Lemmon, Al Pacino, Goldie Hawn, Christopher Walken, Burt Reynolds, George C. Scott, Elizabeth Taylor, Richard Burton, Alec Baldwin, and Patrick Swayze. Katselas was credited with being able to nurture actors with raw talent so that they could develop strong Hollywood careers. He utilized innovative techniques in his courses – one course called “Terrorist Theatre” had a simple premise: successfully get an acting role within six weeks or leave the course.

He grew up in Pittsburgh, Pennsylvania to parents who had immigrated from Greece, and graduated from Carnegie Mellon. He studied acting with Lee Strasberg in New York at the Actors Studio, and received advice from directors Joshua Logan and Elia Kazan.

Katselas was a prominent Scientologist, and a July 2007 profile on Katselas in The New York Times Magazine observed that some of his students stopped taking courses at the Beverly Hills Playhouse because they felt they had been pressured to join the Church of Scientology. According to the article, Katselas credited Scientology founder L. Ron Hubbard “for much of his success in life”, and one of his students works at Scientology’s Celebrity Centre. The article commented that some in Los Angeles view the Beverly Hills Playhouse as “a recruitment center for Scientology”.

Katselas met L. Ron Hubbard after moving to California, and began studying Scientology in 1965. The New York Times Magazine reported that he had reached the level of “Operating Thetan, Level 5, or O.T. V.” in 2007. According to The New York Times Magazine when Scientologists proceed up the “The Bridge to Total Freedom” they learn the story of Xenu, and that: “75 million years ago the evil alien Xenu solved galactic overpopulation by dumping 13.5 trillion beings in volcanoes on Earth, where they were vaporized, scattering their souls.” A Church of Scientology publication, Source, lists Katselas as reaching O.T. V. in 1989.

Though some actors felt pressured to join the Church of Scientology after taking courses at the Beverly Hills Playhouse, at least one individual felt Katselas was not active enough with the organization. Actress Jenna Elfman left the Beverly Hills Playhouse because she felt Katselas was not committed enough to Scientology. Katselas had previously directed Elfman in half of Visions and Lovers: Variations on a Theme, two one-act plays about relationships that he had written himself. In 1999 Katselas had planned to adapt the script of Visions and Lovers to a film version, and Elfman was set to reprise her role from the play. In an article in Variety about the project, Elfman commented on her experience working with Katselas: “He is brilliant, and knows me so well as a person and an actress that he gets the most out of me.”

Other prominent Scientologist actors who have studied under Katselas include Giovanni Ribisi, Jason Lee, and Leah Remini. According to Rolling Stone, Katselas also recruited actress Kelly Preston to Scientology. Actress Nancy Cartwright (the voice of Bart Simpson), told Scientology publication Celebrity that Katselas motivated her to get more active in Scientology, and she stated she took the organization’s “Purification Rundown” and her life “took off completely”.

Anne Archer was introduced to Scientology while studying at the Beverly Hills Playhouse, as was former Scientologist and now outspoken critic actor Jason Beghe. Beghe told Roger Friedman of FOX News in April 2008 that “He [Katselas] gets kickbacks”, and that he was brought to a Scientology center by fellow Beverly Hills Playhouse classmate Bodhi Elfman, Jenna Elfman’s husband. In a 1998 article for Buzz Magazine, Randye Hoder wrote “In his class, Katselas is careful not to label anything as a tenet of Scientology, but there is no question that the church’s influence seeps into the playhouse.”

Anne Archer’s husband and fellow Scientologist, producer Terry Jastrow, commented to The New York Times Magazine that Katselas changed the way he experiences life on a day-to-day basis: “I go out in the world and look at human behavior now. I see a woman or man interacting with a saleslady, and I see the artistry in it. Life is an endless unspooling of art, of acting, of painting, of architecture. And where did I learn that? From Milton.”

Actor Anthony Head of Buffy the Vampire Slayer spoke highly of Katselas in a 2002 interview with San Francisco Chronicle: “He’s this wonderfully intuitive teacher and his premise is basically: The only real barriers are the ones we put in front of ourselves. If you say, ‘My character wouldn’t do that’ — bollocks! Ultimately it’s you who wouldn’t say that. Who knows what your character might do.” In the acknowledgements of her 2004 autobiography Are You Hungry, Dear?: Life, Laughs, and Lasagna, actress Doris Roberts wrote: “I thank my friend and acting teacher, the incredible Milton Katselas, for his insights, wisdom, and inspiration, which have helped make me the actress that I am.”

Katselas authored two books: Dreams Into Action: Getting What You Want, first published in 1996 by Dove Books, and Acting Class: Take a Seat, which came out earlier this month. Dreams Into Action, a New York Times Bestseller, sought to modify motivational acting exercises to the field of business.

In an interview in the 2007 book Acting Teachers of America, Katselas commented on his experiences as an acting teacher over the years: “I have very special teachers here at the Beverly Hills Playhouse—some have been with me for over twenty-five years. I believe that to make a difference over the long haul, we need to train teachers. I really care about the craft of acting. It’s absolutely necessary to take the time and patience to really develop an actor.”

British actor and comedian Sir Norman Wisdom dies aged 95

Tuesday, October 5, 2010 

Tributes are being paid following the announcement late last night that the veteran British actor and comedian Sir Norman Wisdom has died at the age of 95.

He passed away peacefully at the Abbot’s Wood nursing home, Ballasalla, Isle of Man yesterday evening. Following a series of strokes over the last 6 months, his health had declined severely.

Sir Norman’s career spanned almost seven decades, during which time he starred in 19 films, and 38 sitcoms, most as the inept character “Pitkin”, the persistant thorn in the side of his boss, Mr. Grimsdale. His most well known serious role came in the television play Going Gently in 1981, for ITV, in which he played a patient in hospital suffering from terminal cancer.

Following the news, the Albanian Ambassador in the UK, Zef Mazi explained that Sir Norman’s death was covered on all the news channels in Albania, where he was exceptionally popular. His material was the only Western-style comedy permitted to be shown in the Communist country. “After Charlie Chaplin, he was the biggest comedy star in Albania. I still remember his character Pitkin and his boss Mr Grimsdale,” he said. “He was very popular with everyone from very young people to very old people and he made us laugh at a time, in the communist period, when there were not many reasons to laugh.”

The Isle of Man’s Chief Minister, Tony Brown MHK, said that he was “deeply saddened” to have heard of the death. He is quoted as having said “[w]e were very fortunate indeed that Sir Norman chose to make the Isle of Man his home. He was a wonderful asset to the local community and made a tremendous contribution to countless Island charities and good causes.”

He was knighted by Queen Elizabeth II in her conferred role as Lord of Mann on his 90th birthday in 2005, at the same time being made a Freeman of the Borough of Douglas.

The announcement of Sir Norman’s death was confirmed by his son and family in a statement last night.

Caribou plays the Bowery Ballroom

Tuesday, November 6, 2007 

Daniel Snaith, better known as Caribou, formerly known as Manitoba until a lawsuit by musician Richard “Handsome Dick” Manitoba, recently played New York City’s Bowery Ballroom. Below is Wikinews reporter David Shankbone’s conversation with the electronica pioneer.

David Shankbone: How is the tour going?

DS: How do European and American audiences compare to each other?

DS: But they are more electronic in Europe than they are here, right?

DS: You reach the same fans in each place?

DS: Do you play to larger audiences over there or here?

DS: Do you have a favorite venue?

DS: What would be a dream venue to play?

DS: Is there a continent you haven’t played where you would like to?

DS: Rio or São Paulo?

DS: How has the Iraq War affected you as an artist?

DS: Has it affected you as a person?

DS: Do you find you’re more inspired by manmade things or things in nature?

DS: What sort of ideas inspire you?

DS: Would you consider your music to be mathematical?

DS: Do you have a favorite mathematician or unsolved mathematical problem?

DS: What’s a trait you deplore in other people?

DS: What’s a trait you deplore in yourself?

DS: You think that might be a negative?

DS: That’s a challenge for any human of whether or not to pursue something you think is a greater good or indulge yourself. How do you wrestle with that question?

DS: Well, we need music in this world and if people are responding to it, you’re giving something to them.

DS: Maybe. [Laughs] Hillary or Barack?

DS: What do you think of Gordon Brown?

DS: What would be a bigger turn-off for you in bed, someone who was overly flatulent, or someone who spoke in a baby voice?

DS: Do you have a favorite curse word?

DS: Favorite euphemism for breasts?

DS: If you had to choose between the destruction of the entire continent of Africa or the entire continent of Asia, which would you choose?

DS: What are traits you respect in a woman?

DS: It doesn’t differ in men?

DS: What’s your most treasured possession?

DS: Any favorite films?

DS: What difficult question in an interview do you anticipate but are never asked?

DS: What question are you tired of answering?

DS: In the last year, where have you drawn most of your influence, and you can’t have been listening to them beyond a year ago.

Black Storm 60x Auto Dark Bronzer Review

Black Storm 60x Auto Dark Bronzer Review

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artiwizi1

From the many auto dark bronzer solutions available on the market, Black Storm 60x is definitely the cheapest one that can be known as a professional product. Now, a lot of you will end up deterred because of the low cost, but as it turns out this actually is a impressive product and it provides with two very important benefits. First would obviously be the bronzing which is actually nothing short of amazing, considering which other products take ages to achieve the same shade of brown. Black Storm also provides amazing skin moisturizing action, which makes it the perfect product in case you are looking for a quick and healthy tan.

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One thing that sets Black Storm 60x apart from the rest is the Special components which promote the production of melanin by allowing more UV light to enter to the skin. This means that you can actually tan, while wearing fake tanner. This is revolutionary in the industry.

The Silicone formula glides onto skin keeping it constantly smooth and luxurious feeling.

The smell is actually awesome too. If you are not usually wearing a specific sort of cologne the smell which is actually given by Black Storm should probably be adequate, and that means you are conserving some money in this factor as well.

In summary I will only say that I have been very pleased with the results of Black Storm 60x and I am confident other people which have used this system have only positive items to report. So, I will only recommend Black Storm 60x Auto Dark Bronzerfor those of you that are trying to find a good tan that is possible to constantly achieve. Black Storm Review

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NASCAR driver Labonte terminates deal with TRG Motorsports

Friday, June 25, 2010 

On Tuesday, NASCAR Sprint Cup Series driver Bobby Labonte ended his contract with TRG Motorsports because of the possibility of becoming a “start and park” racer because the team could not find sponsorship. Labonte said, “I just don’t want to do it, I don’t want to do the start and park thing.” The move became public earlier this week.

After leaving the team, Labonte will drive for Robby Gordon Motorsports in New Hampshire this weekend, then for Phoenix Racing for the following two events. Robby Gordon said Labonte may be able to race later in the summer, but for now it is a one race only deal. Labonte also stated, “We didn’t have the success that we really wanted, and kind of got to the point where Kevin was in a position that he was going to have to do some start and park races”.

Gordon hopes to have Labonte in the car for more races, so his team can learn from the former Sprint Cup Series Drivers’ Championship winner.